Season 1: Brilliant and passionate the 25 year old Leonardo da Vinci is an artist, inventor to swordsman, lover, dreamer and idealist. Gifted with visionary intellect and talent that ware almost superhuman, Leonardo struggles to live within the confines of his own reality and time. When a chance meeting with a mysterious stranger throws his world into turmoil, he and his companions find themselves in the midst of a storm that has been brewing for centuries; a conflict of truth and lies, religion and reason, past and future. It seems only the shadowy cult of the Sons of Mithras and the power of the Vatican hold the key to the truth about Leonardo's past--and his future. A hero armed only with genius and invention, Leonardo must take up the fight against foes who use history to suppress the truth.
Season 2: Florence has been thrown into chaos in the wake of the Pazzi conspiracy and Leonardo da Vinci must push the limits of his mind and body to defend the city against the forces of Rome. When the dust settles, friends are buried and rivalries enflamed. While the Medicis are forced to go to unthinkable lengths to deal with new threats, da Vinci continues on his quest to find the fabled Book of Leaves and uncover the secret history of his mother. As he comes to realise that he has lethal competition in his quest--new enemies who may be even worse than the forces of Pope Sixtus--his search takes him to faraway lands and forces him to re-evaluate everything he knew about the world and his own history.